Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.49 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518330 | 0.84 | BCAT2 (0.41) | GABBR2GABBR1BCAT2TAAR1HTR2A | |
| Hydrochloric Acid SCHEMBL6947022 | 0.80 | GABBR2 (0.56) | GABBR2GABBR1BCAT2MTNR1AMTNR1B | |
| SCHEMBL20773797 | 0.80 | GABBR2 (0.59) | GABBR2GABBR1BCAT2TAAR1HTR2A | |
| SCHEMBL3921879 | 0.78 | BCAT2 (0.68) | BCAT2TAAR1CYP2D6SMN1; SMN2AOC3 | |
| SCHEMBL21408380 | 0.78 | GBA1 (0.46) | BCAT2AOC3KDM4EL3MBTL1 | |
| SCHEMBL14769096 | 0.78 | BCAT2 (0.68) | BCAT2TAAR1CYP2D6SMN1; SMN2AOC3 | |
| SCHEMBL1985542 | 0.77 | MTNR1A (0.69) | GABBR2GABBR1BCAT2TAAR1HTR2A | |
| SCHEMBL4018230 | 0.76 | AOC3 (0.58) | BCAT2TAAR1SMN1; SMN2AOC3 | |
| SCHEMBL17198959 | 0.76 | AOC3 (0.58) | BCAT2TAAR1SMN1; SMN2AOC3 | |
| SCHEMBL1983010 | 0.76 | NPC1 (0.63) | GABBR2GABBR1BCAT2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709032-A | VASODILATION AND HYPOTENSIVE AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1987-11-24 | — | — | US | disclosed |
| US-4634770-A | VASODILATORS, HYPOTENSIVES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1987-01-06 | — | — | US | disclosed |
| EP-0109023-A1 | Isoquinolinesulfonamide derivatives and process for the preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-05-23 | — | — | EP | disclosed |