Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240854 | 0.85 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2SIGMAR1 | |
| SCHEMBL8933621 | 0.84 | MTNR1A (0.52) | MTNR1AMTNR1BIDH1NQO2SIGMAR1 | |
| SCHEMBL9971034 | 0.83 | MTNR1A (0.61) | MTNR1AMTNR1BIDH1NQO2SIGMAR1 | |
| SCHEMBL8485078 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1BIDH1NQO2SIGMAR1 | |
| SCHEMBL2171722 | 0.80 | SLC2A1 (0.42) | MTNR1AMTNR1BIDH1CYP1A2CYP2A6 | |
| SCHEMBL4749570 | 0.79 | MTNR1A (0.60) | MTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL3277526 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BIDH1NQO2SIGMAR1 | |
| SCHEMBL15345391 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BIDH1SIGMAR1CYP1A2 | |
| SCHEMBL1012628 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BIDH1NQO2SIGMAR1 | |
| SCHEMBL6856603 | 0.79 | MTNR1A (0.59) | MTNR1AMTNR1BIDH1NQO2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |