Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844609 | 0.90 | NPC1 (0.48) | NPC1USP2MEN1KMT2APOLB | |
| SCHEMBL5395538 | 0.75 | ALDH1A1 (0.50) | NPC1USP2MEN1KMT2APOLB | |
| SCHEMBL5387895 | 0.75 | ALDH1A1 (0.50) | NPC1USP2MEN1KMT2APOLB | |
| SCHEMBL8370418 | 0.73 | ALDH1A1 (0.48) | NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1913754 | 0.72 | HCRTR1 (0.44) | HCRTR1NPC1USP2MEN1KMT2A | |
| SCHEMBL9141452 | 0.72 | HCRTR1 (0.44) | HCRTR1NPC1USP2MEN1KMT2A | |
| SCHEMBL9144052 | 0.71 | HCRTR1 (0.42) | HCRTR1NPC1USP2MEN1KMT2A | |
| SCHEMBL7146525 | 0.71 | HCRTR1 (0.45) | HCRTR1NPC1USP2MEN1KMT2A | |
| SCHEMBL16340796 | 0.71 | HCRTR1 (0.42) | HCRTR1NPC1USP2MEN1KMT2A | |
| SCHEMBL2796237 | 0.70 | HTT (0.54) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055475-A1 | GUANIDINE DERIVIATIVES AS INHIBITORS OF NA+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |