SCHEMBL8370418

SCHEMBL8370418

O=C(O)C1CCC(C(=O)O)c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
EDNRA P25101 2/20 0.45
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.41
EDNRB P24530 1/20 0.41
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CDC42 P60953 3/20 0.40
RAC1 P63000 3/20 0.40
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
NPC1 O15118 1/20 0.40
CHRM3 P20309 1/20 0.40
OPRM1 P35372 1/20 0.40
RAB9A P51151 1/20 0.40
PAK1 Q13153 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19762837 0.89 ALDH1A1 (0.42) ALDH1A1EDNRAAKR1C3AKR1C1EDNRB
SCHEMBL11002346 0.88 NOTUM (0.42) ALDH1A1EDNRAAKR1C3AKR1C1TSHR
SCHEMBL432906 0.85 ALDH1A1 (0.48) ALDH1A1EDNRAAKR1C3AKR1C1EDNRB
SCHEMBL10706985 0.83 ACP3 (0.40) ALDH1A1EDNRACDC42RAC1PTGS1
SCHEMBL11788825 0.83 ALDH1A1 (0.38) ALDH1A1EDNRAAKR1C3AKR1C1CYP2C19
SCHEMBL16885255 0.83 NPC1 (0.43) ALDH1A1EDNRACDC42RAC1PTGS1
SCHEMBL907688 0.81 PIN1 (0.60) TSHRNPSR1
SCHEMBL12431131 0.81 PIN1 (0.60) TSHRNPSR1
SCHEMBL2790690 0.81 PIN1 (0.60) TSHRNPSR1
SCHEMBL1400973 0.81 PIN1 (0.60) TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12157094-B2 Gas separation method with multilayer membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-12-03 US claimed
US-12138596-B2 Method for separating carbon dioxide and methane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-11-12 US claimed
US-12102967-B2 Method for separating a gas stream to isolate carbon dioxide KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US claimed
US-12102966-B2 CO2 gas enrichment method KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US claimed
US-20240278190-A1 GAS SEPARATION METHOD WITH MULTILAYER MEMBRANE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-22 US claimed
US-20240278188-A1 METHOD FOR SEPARATING CARBON DIOXIDE AND METHANE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-22 US claimed
US-20240269622-A1 METHOD FOR SEPARATING A GAS STREAM TO ISOLATE CARBON DIOXIDE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-15 US claimed
US-20240226816-A1 CO2 GAS ENRICHMENT METHOD KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-07-11 US claimed
US-11969694-B2 Method for separating a gas mixture KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-30 US claimed
US-11964240-B2 Gas filter for separating gaseous compositions KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-23 US claimed
US-20230173434-A1 METHOD FOR SEPARATING A GAS MIXTURE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-06-08 US claimed
US-20230149860-A1 GAS FILTER FOR SEPARATING GASEOUS COMPOSITIONS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-05-18 US claimed
US-11571665-B2 Layered CDC-polyamide membrane and its make and use KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-02-07 US claimed
US-20200206695-A1 LAYERED CDC-POLYAMIDE MEMBRANE AND ITS MAKE AND USE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-07-02 US claimed
WO-1999061506-A1 THERMOSETTING COATING COMPOSITIONS BASED ON POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO claimed
US-12157094-B2 Gas separation method with multilayer membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-12-03 US disclosed
US-12138596-B2 Method for separating carbon dioxide and methane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-11-12 US disclosed
WO-2014051021-A9 1, 4-TETRALIN DICARBOXYLIC ACID DIALKYL ESTER AND METHOD FOR PRODUCING SAME 三菱瓦斯化学株式会社 (JP) 2014-08-07 WO disclosed
WO-2014051021-A1 1, 4-TETRALIN DICARBOXYLIC ACID DIALKYL ESTER AND METHOD FOR PRODUCING SAME 三菱瓦斯化学株式会社 (JP) 2014-04-03 WO disclosed
WO-1999061506-A1 THERMOSETTING COATING COMPOSITIONS BASED ON POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO disclosed