Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775969 | 0.92 | TP53 (0.43) | ESR1ESR2MEN1KMT2ACNR1 | |
| SCHEMBL6171046 | 0.86 | CD274 (0.44) | ESR1ESR2MEN1KMT2AF2 | |
| SCHEMBL6172000 | 0.84 | ESR1 (0.61) | ESR1ESR2MEN1KMT2ACNR1 | |
| SCHEMBL6171904 | 0.80 | ESR1 (0.56) | ESR1ESR2CNR1CNR2F2 | |
| SCHEMBL6597618 | 0.79 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL6172361 | 0.79 | HTR6 (0.41) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL6171651 | 0.79 | EGFR (0.42) | ESR1ESR2CNR1CNR2BCHE | |
| SCHEMBL7447061 | 0.78 | KMT2A (0.62) | MEN1KMT2AL3MBTL1ACHEMCHR1 | |
| SCHEMBL7775991 | 0.77 | ESR1 (0.55) | ESR1ESR2CNR1CNR2F2 | |
| SCHEMBL7768296 | 0.76 | ESR1 (0.71) | ESR1ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |