Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.69 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.69 |
| ▸ | F10 | P00742 | 4/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564999 | 0.87 | IDO1 (0.57) | NOD2NOD1F10GABRA1GABRA5 | |
| SCHEMBL4798323 | 0.87 | NOD2 (0.85) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL7423858 | 0.83 | CCR2 (0.74) | F10GABRA1GABRA5KMT2AIDO1 | |
| SCHEMBL6302610 | 0.81 | NOD2 (0.84) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6307843 | 0.81 | NOD2 (0.74) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6706704 | 0.80 | NOD2 (0.82) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL12948823 | 0.80 | NOD2 (0.82) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL5421098 | 0.80 | NOD2 (0.82) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL11004197 | 0.79 | NOD2 (0.50) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6858374 | 0.79 | NOD2 (0.80) | NOD2NOD1F10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |