Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 6/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722465 | 0.87 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL2962631 | 0.83 | OPRM1 (0.55) | OPRL1MEN1KMT2ACCR3NPSR1 | |
| SCHEMBL3583059 | 0.82 | OPRL1 (0.63) | OPRL1ALDH1A1 | |
| SCHEMBL8507420 | 0.82 | OPRL1 (0.63) | OPRL1ALDH1A1 | |
| SCHEMBL1205831 | 0.82 | OPRL1 (0.63) | OPRL1ALDH1A1 | |
| SCHEMBL11504609 | 0.81 | CYP1A2 (0.68) | OPRL1MEN1KMT2ACCR3KDM4E | |
| SCHEMBL11651599 | 0.81 | OPRL1 (0.58) | OPRL1ALDH1A1 | |
| SCHEMBL8074161 | 0.80 | CYP1A2 (0.66) | OPRL1MEN1KMT2AALDH1A1 | |
| SCHEMBL13039159 | 0.80 | CYP1A2 (0.66) | OPRL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8074159 | 0.80 | CYP1A2 (0.66) | OPRL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044334-A2 | NOVEL PIPERAZINE OR HOMOPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THEIR PREPARATION | EGIS Gyógyszergyár Rt. (HU) | 1997-11-27 | — | — | WO | disclosed |