SCHEMBL2962631

SCHEMBL2962631

CCC(c1ccccc1)N1CCN(c2ccccc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.55
OPRD1 P41143 2/20 0.55
OPRK1 P41145 2/20 0.55
OPRL1 P41146 2/20 0.55
LMNA P02545 1/20 0.54
CHRNA7 P36544 1/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
GFER P55789 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
CCR3 P51677 4/20 0.51
DRD2 P14416 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
MC4R P32245 3/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2962625 0.89 OPRM1 (0.65) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL13835660 0.85 DRD2 (0.55) OPRM1OPRD1OPRK1OPRL1LMNA
SCHEMBL9378695 0.84 LMNA (0.47) OPRM1OPRD1LMNACHRNA7ALDH1A1
SCHEMBL7424307 0.83 ADRA2A (0.57) OPRL1KDM4EALDH1A1GFERL3MBTL1
SCHEMBL14593276 0.82 MC4R (0.69) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL8916036 0.82 CYP1A2 (0.62) OPRM1OPRD1OPRK1OPRL1LMNA
SCHEMBL30363975 0.82 OPRM1 (0.61) OPRM1OPRD1OPRK1OPRL1ALDH1A1
SCHEMBL1964502 0.82 CYP1A2 (0.62) OPRM1OPRD1OPRK1OPRL1LMNA
SCHEMBL30364119 0.82 OPRM1 (0.61) OPRM1OPRD1OPRK1OPRL1ALDH1A1
SCHEMBL11504609 0.81 CYP1A2 (0.68) OPRM1OPRD1OPRK1OPRL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118948735-A Short-time dissolving microneedle 考司美德制药株式会社 2024-11-15 CN disclosed
EP-4129392-A1 FAST-DISSOLVING MICRONEEDLE Cosmed Pharmaceutical Co., Ltd. (JP) 2023-02-08 EP disclosed
CN-115397401-A Adhesive sheet for skin 考司美德制药株式会社 2022-11-25 CN disclosed
US-20220233833-A1 FAST-DISSOLVING MICRONEEDLE COSMED PHARMACEUTICAL CO., LTD. (JP) 2022-07-28 US disclosed
CN-113766913-A Short time dissolving microneedle 考司美德制药株式会社 2021-12-07 CN disclosed
EP-2116224-B1 COSMETIC COMPOSITION JNC CORP (JP) 2016-01-27 EP disclosed
US-20100055060-A1 COSMETIC COMPOSITION JNC CORPORATION (JP) 2010-03-04 US disclosed
EP-2116224-A1 COSMETIC COMPOSITION Chisso Corporation (JP) 2009-11-11 EP disclosed
EP-1604647-B1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof CHISSO CORP (JP) 2008-05-07 EP disclosed
US-20060018867-A1 Cosmetic composition and production thereof ICHIMARU PHARCOS CO., LTD 2006-01-26 US disclosed
EP-1604647-A1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof Ichimaru Pharcos Co., Ltd. (JP) 2005-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018867-A1 Cosmetic composition and production thereof CUTA, PARG, TYR OPRM1 2226/4885OPRD1 1398/4885OPRK1 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.