Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308256 | 0.95 | CYP26A1 (0.55) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL12308250 | 0.90 | CA1 (0.55) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL12334493 | 0.90 | CA2 (0.54) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL12308244 | 0.90 | TAS1R3 (0.43) | CYP26A1CA1CA2GAARAB9A | |
| SCHEMBL12574370 | 0.88 | TAS1R3 (0.47) | CYP26A1GAATAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL12308202 | 0.86 | TAS1R3 (0.55) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL12308271 | 0.86 | P4HTM (0.45) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL12574343 | 0.83 | CA1 (0.47) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL12308229 | 0.83 | TAS1R3 (0.46) | CYP26A1CA1CA2CA12CA9 | |
| SCHEMBL29809632 | 0.82 | ECE1 (0.54) | CYP26A1L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140128571-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140128571-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-05-08 | — | — | US | disclosed |
| US-20130165630-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165630-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-06-27 | — | — | US | disclosed |
| US-20120302780-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302780-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-20110237776-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2011-09-29 | — | — | US | disclosed |
| US-20110237776-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302780-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | CBS, ARSA, SOD1 | CYP26A1 2288/4885CA1 4540/4885CA2 3850/4885 |
| US-20140128571-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | SOD1, CBS, ABCB7 | CYP26A1 2219/4885CA1 4408/4885CA2 3589/4885 |
| US-20110237776-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | SOD1, CBS, ABCB7 | CYP26A1 2219/4885CA1 4408/4885CA2 3589/4885 |
| US-20130165630-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | SOD1, CBS, ABCB7 | CYP26A1 2219/4885CA1 4408/4885CA2 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.