Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 12/20 | 0.76 |
| ▸ | PDE4A | P27815 | 10/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.76 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.58 |
| ▸ | PDE1A | P54750 | 1/20 | 0.58 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.58 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19083721 | 0.86 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7477234 | 0.86 | PDE4D (0.82) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL29802080 | 0.86 | KMT2A (0.78) | MEN1KMT2A | |
| SCHEMBL15595269 | 0.86 | KMT2A (0.78) | MEN1KMT2A | |
| SCHEMBL7458162 | 0.84 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL19075717 | 0.81 | PDE4A (0.74) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7424332 | 0.79 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7423857 | 0.79 | PDE4D (0.82) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL20589963 | 0.78 | EPHX2 (1.00) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7364116 | 0.78 | PDE4B (0.56) | PDE4DPDE4APDE4BPDE4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | claimed |
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | disclosed |