Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241918 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| SCHEMBL27911501 | 0.78 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| SCHEMBL11605746 | 0.77 | CYP1A2 (0.75) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| Bromide SCHEMBL3103373 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL18271203 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| SCHEMBL4168758 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| SCHEMBL28782824 | 0.75 | CYP1A2 (0.55) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| SCHEMBL302557 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C19CYP3A4HSD17B10 | |
| SCHEMBL30447073 | 0.74 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 | |
| SCHEMBL8099994 | 0.74 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2C19HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0837071-A1 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0685489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5430023-A | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5252566-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0542525-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0479489-A2 | Tripeptide antithrombotic agents | ELI LILLY AND COMPANY (US) | 1992-04-08 | — | — | EP | disclosed |
| US-4490370-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-12-25 | — | — | US | disclosed |