Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426141 | 0.88 | TAAR1 (0.38) | TAAR1SIGMAR1DAOKMT2AMEN1 | |
| SCHEMBL7419980 | 0.81 | AOC3 (0.46) | AOC3TAAR1SLC2A1MAPK1MAPT | |
| SCHEMBL7426730 | 0.79 | AOC3 (0.43) | AOC3TAAR1SLC2A1MAPK1KMT2A | |
| SCHEMBL7429670 | 0.78 | ACKR3 (0.35) | AOC3TAAR1DAOKMT2AKDM4E | |
| SCHEMBL5869287 | 0.77 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL5869299 | 0.77 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL5869290 | 0.77 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL7421892 | 0.76 | NR4A2 (0.51) | — | |
| SCHEMBL7430634 | 0.76 | AOC3 (0.39) | AOC3TAAR1SLC2A1MAPK1 | |
| SCHEMBL3681437 | 0.74 | ACE2 (0.48) | KDM4EEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |