Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426730 | 0.98 | AOC3 (0.43) | AOC3TAAR1SLC2A1MAPK1 | |
| SCHEMBL7419980 | 0.94 | AOC3 (0.46) | AOC3TAAR1SLC2A1MAPK1 | |
| SCHEMBL7419020 | 0.90 | GRN (0.38) | AOC3GRNSORT1MMP3TACR1 | |
| SCHEMBL7422595 | 0.86 | RXRA (0.40) | AOC3GRNSORT1MAPK1ADAMTS5 | |
| SCHEMBL7424530 | 0.84 | LTB4R (0.44) | — | |
| SCHEMBL7419478 | 0.80 | MMP2 (0.42) | GRNSORT1MMP3ADAMTS5 | |
| SCHEMBL7378945 | 0.80 | MEN1 (0.48) | AOC3TAAR1MMP1MMP3 | |
| SCHEMBL7421892 | 0.80 | NR4A2 (0.51) | — | |
| SCHEMBL7417819 | 0.78 | HDAC1 (0.34) | GRNSORT1 | |
| SCHEMBL7424617 | 0.78 | MAOB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |