Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424533 | 0.88 | AOC3 (0.39) | TAAR1MEN1KMT2ASIGMAR1DAO | |
| SCHEMBL7429670 | 0.82 | ACKR3 (0.35) | TAAR1MEN1KMT2ACASRDAO | |
| SCHEMBL5870188 | 0.77 | MMP1 (0.48) | MMP1MMP3MMP9ANPEPSLC6A3 | |
| SCHEMBL5870191 | 0.77 | MMP1 (0.48) | MMP1MMP3MMP9ANPEPSLC6A3 | |
| SCHEMBL5869703 | 0.77 | MMP1 (0.48) | MMP1MMP3MMP9ANPEPSLC6A3 | |
| SCHEMBL3714337 | 0.74 | CYP11B1 (0.41) | TAAR1ANPEPCYP2D6CYP2C9ALOX15 | |
| SCHEMBL7426149 | 0.73 | MMP1 (0.42) | MMP1MMP3MMP9ANPEPCRHBP | |
| SCHEMBL7427123 | 0.72 | LTB4R (0.44) | KMT2ACYP2D6 | |
| SCHEMBL7378945 | 0.72 | MEN1 (0.48) | TAAR1MMP1MMP3MMP9MEN1 | |
| SCHEMBL3711705 | 0.69 | CYP11B1 (0.41) | MMP1MMP3MMP9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |