Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426730 | 0.97 | AOC3 (0.43) | AOC3TAAR1SLC2A1MAPK1ALDH1A1 | |
| SCHEMBL7430634 | 0.94 | AOC3 (0.39) | AOC3TAAR1SLC2A1MAPK1 | |
| SCHEMBL7421892 | 0.85 | NR4A2 (0.51) | — | |
| SCHEMBL7419020 | 0.83 | GRN (0.38) | AOC3ALDH1A1TSHR | |
| SCHEMBL7422595 | 0.83 | RXRA (0.40) | AOC3MAPK1 | |
| SCHEMBL7424533 | 0.81 | AOC3 (0.39) | AOC3TAAR1SLC2A1MAPK1ALDH1A1 | |
| SCHEMBL7378945 | 0.81 | MEN1 (0.48) | AOC3TAAR1KMT2AMEN1HPGD | |
| SCHEMBL7424530 | 0.81 | LTB4R (0.44) | — | |
| SCHEMBL7427483 | 0.80 | SLC1A5 (0.54) | PTGER4PTGER2SLC6A9 | |
| SCHEMBL3681437 | 0.79 | ACE2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |