Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421897 | 0.93 | NR4A2 (0.49) | MAPK1NR4A2PKMMAOAMAOB | |
| SCHEMBL7424457 | 0.92 | NR4A2 (0.48) | MAPK1GRNSORT1KMT2AMEN1 | |
| SCHEMBL7425598 | 0.89 | KMT2A (0.41) | KMT2AMEN1CTSKALOX5SMN1; SMN2 | |
| SCHEMBL7424624 | 0.89 | GRN (0.44) | MAPK1GRNSORT1KMT2AMEN1 | |
| SCHEMBL7427134 | 0.88 | MEN1 (0.41) | KMT2AMEN1NR4A2MAOAMAOB | |
| SCHEMBL7426645 | 0.86 | GPR132 (0.50) | KMT2AMEN1CTSKALOX5SMN1; SMN2 | |
| SCHEMBL7424286 | 0.85 | NR4A2 (0.49) | KMT2AMEN1NR4A2MAOAMAOB | |
| SCHEMBL7420340 | 0.84 | MAPT (0.44) | CTSKMME | |
| SCHEMBL7430645 | 0.83 | GRN (0.44) | MAPK1GRNSORT1MMEACE | |
| SCHEMBL7422599 | 0.82 | GRN (0.47) | MAPK1GRNSORT1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |