Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424536 | 0.85 | MAPK1 (0.42) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL7424457 | 0.85 | NR4A2 (0.48) | NR4A2GPR132MAOBMAOAMEN1 | |
| SCHEMBL7421897 | 0.84 | NR4A2 (0.49) | NR4A2NPC1RAB9AMAOBMAOA | |
| SCHEMBL7420340 | 0.83 | MAPT (0.44) | RAB9A | |
| SCHEMBL7425598 | 0.82 | KMT2A (0.41) | GPR132MEN1KMT2A | |
| SCHEMBL7428942 | 0.81 | KEAP1 (0.40) | NR4A2 | |
| SCHEMBL7427134 | 0.81 | MEN1 (0.41) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL7426645 | 0.81 | GPR132 (0.50) | GPR132MEN1KMT2A | |
| SCHEMBL5870205 | 0.78 | NR4A2 (0.51) | NR4A2NPC1RAB9ALNPEPGPR132 | |
| SCHEMBL5869323 | 0.78 | NR4A2 (0.51) | NR4A2NPC1RAB9ALNPEPGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |