Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180733 | 0.79 | EPHX1 (0.51) | DPP4TACR1EPHX1ALDH1A1CYP1A2 | |
| SCHEMBL18657232 | 0.74 | GAA (0.58) | GAAKDM4E | |
| SCHEMBL6265947 | 0.74 | EPHX1 (0.46) | DPP4DPP7TACR1EPHX1CYP1A2 | |
| SCHEMBL4022907 | 0.74 | EPHX1 (0.46) | DPP4DPP7TACR1EPHX1CYP1A2 | |
| SCHEMBL27832973 | 0.72 | CPN1 (0.45) | DPP4TACR1EPHX1 | |
| SCHEMBL24652524 | 0.72 | ALDH1A1 (0.57) | GAAALDH1A1TSHR | |
| SCHEMBL3165125 | 0.72 | ALDH1A1 (0.57) | GAAALDH1A1TSHR | |
| SCHEMBL4281407 | 0.71 | GAA (0.64) | GAAALDH1A1KDM4E | |
| SCHEMBL4156781 | 0.70 | EPHX1 (0.43) | TACR1EPHX1 | |
| SCHEMBL4156782 | 0.70 | EPHX1 (0.43) | TACR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898562-A1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997032846-A1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |