Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TACR3 | P29371 | 1/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.55 |
| ▸ | CCR3 | P51677 | 2/20 | 0.54 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281407 | 0.91 | GAA (0.64) | GAACARM1PRMT6CCR3PRMT3 | |
| SCHEMBL19382678 | 0.85 | GRIN2D (0.56) | TACR3CARM1PRMT6CCR3GRIN2B | |
| SCHEMBL3867284 | 0.79 | PRMT3 (0.66) | GAACARM1PRMT6CCR3PRMT3 | |
| SCHEMBL21763292 | 0.79 | TACR3 (0.71) | GAATACR3 | |
| SCHEMBL4023997 | 0.78 | GRIN2B (0.66) | GAACARM1PRMT6CCR3PRMT3 | |
| SCHEMBL27332314 | 0.78 | CTSS (0.53) | ACHE | |
| SCHEMBL23719076 | 0.78 | CCR3 (0.80) | GAACARM1PRMT6CCR3PRMT3 | |
| SCHEMBL8262506 | 0.78 | CCR3 (0.80) | GAACARM1PRMT6CCR3PRMT3 | |
| SCHEMBL6218861 | 0.78 | CCR3 (0.80) | GAACARM1PRMT6CCR3PRMT3 | |
| SCHEMBL5888792 | 0.77 | HTR7 (0.68) | CARM1PRMT6CCR3PRMT3PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393794-B1 | DESIGN, SYNTHESIS AND EVALUATION OF PROCASPASE ACTIVATING COMPOUNDS AS PERSONALIZED ANTI-CANCER DRUGS | UNIV ILLINOIS (US) | 2017-03-22 | — | — | EP | disclosed |