Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435226 | 1.00 | FKBP1A (0.58) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL6436090 | 0.92 | FKBP1A (0.62) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL7426375 | 0.92 | FKBP1A (0.62) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL22209491 | 0.91 | ALDH1A1 (0.61) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL18620867 | 0.91 | ALDH1A1 (0.61) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL22209524 | 0.89 | FKBP1A (0.61) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL18620608 | 0.89 | FKBP1A (0.61) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL24066782 | 0.89 | CTSL (0.60) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL20484565 | 0.88 | ACE (0.61) | FKBP1ATSHRALDH1A1CYP3A4ACE | |
| SCHEMBL18620600 | 0.88 | ACE (0.61) | FKBP1ATSHRALDH1A1CYP3A4ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |