Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 10/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740465 | 0.84 | HRH4 (0.48) | HRH4HRH3F10F2CYP51A1 | |
| SCHEMBL741493 | 0.84 | SMYD3 (0.45) | HRH4HRH3CYP51A1PYGL | |
| SCHEMBL741864 | 0.82 | SMYD3 (0.42) | CYP51A1PYGLMEN1RAB9AKMT2A | |
| SCHEMBL4089036 | 0.82 | F10 (0.59) | HRH4HRH3F10F2 | |
| SCHEMBL4089034 | 0.82 | F10 (0.59) | HRH4HRH3F10F2 | |
| Hydrochloric Acid SCHEMBL741427 | 0.76 | HRH4 (0.48) | HRH4HRH3F10F2CYP51A1 | |
| SCHEMBL743192 | 0.76 | F10 (0.46) | F10F2CYP51A1PYGL | |
| Hydrochloric Acid SCHEMBL742844 | 0.76 | F10 (0.50) | F10F2 | |
| SCHEMBL740569 | 0.76 | F10 (0.72) | F10F2 | |
| Hydrochloric Acid SCHEMBL739327 | 0.76 | F10 (0.52) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-B1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |