Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047340 | 0.89 | GAA (0.75) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL7421567 | 0.88 | KDM4E (0.63) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL7428268 | 0.84 | HTT (0.65) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL12793852 | 0.83 | ALDH1A1 (0.78) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL29531346 | 0.83 | ALDH1A1 (0.78) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL7415584 | 0.80 | SMN1; SMN2 (0.78) | SMN1; SMN2HTTLMNATSHRKMT2A | |
| SCHEMBL14712377 | 0.79 | PRMT1 (0.66) | GAASMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL29530578 | 0.78 | PRMT1 (0.74) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL9305676 | 0.78 | PRMT1 (0.74) | GAASMN1; SMN2HTTLMNATSHR | |
| SCHEMBL7425706 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTLMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |