Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.64 |
| ▸ | GALR3 | O60755 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912767 | 0.89 | SMN1; SMN2 (0.81) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL7415584 | 0.86 | SMN1; SMN2 (0.78) | SMN1; SMN2HTTRAB9ALMNAPKM | |
| SCHEMBL7425436 | 0.84 | PKM (0.82) | SMN1; SMN2HTTPKMALDH1A1 | |
| SCHEMBL7423847 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTRAB9ALMNAPKM | |
| SCHEMBL7428268 | 0.79 | HTT (0.65) | SMN1; SMN2HTTRAB9ALMNAPKM | |
| SCHEMBL4182162 | 0.79 | KMT2A (0.77) | SMN1; SMN2HTTLMNAALDH1A1MAPK1 | |
| SCHEMBL7425093 | 0.79 | PKM (0.66) | SMN1; SMN2HTTRAB9APKMALDH1A1 | |
| SCHEMBL7420203 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTRAB9ALMNAPKM | |
| SCHEMBL17456893 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTRAB9ANPC1LMNA | |
| SCHEMBL7425459 | 0.77 | GAA (0.80) | SMN1; SMN2HTTLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |