Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 5/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474586 | 0.92 | PDE4B (0.50) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL7417915 | 0.77 | PDE4B (0.52) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL15532207 | 0.76 | PDE4B (0.69) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL9526223 | 0.75 | PDE4B (0.68) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL5083406 | 0.73 | PDE4D (0.45) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL7425565 | 0.71 | PDE4D (0.59) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL30614148 | 0.70 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7542303 | 0.70 | GFER (0.48) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL14532456 | 0.69 | PDE4B (0.49) | PDE4BPDE4DGFERPDE4APDE4C | |
| SCHEMBL4544198 | 0.68 | PDE4B (0.71) | PDE4BPDE4DGFERPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | claimed |
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |