Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.51 |
| ▸ | PDE4A | P27815 | 5/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15532207 | 0.82 | PDE4B (0.69) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL9526223 | 0.81 | PDE4B (0.68) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL7417912 | 0.80 | PDE4D (0.69) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL14477305 | 0.77 | KDM2B (0.50) | TYK2 | |
| SCHEMBL7474586 | 0.77 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL7425561 | 0.77 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CGFER | |
| SCHEMBL7423445 | 0.74 | KDM2B (0.50) | — | |
| SCHEMBL4839335 | 0.72 | KDM2B (0.50) | — | |
| SCHEMBL30614148 | 0.72 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL5083406 | 0.71 | PDE4D (0.45) | PDE4BPDE4DPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |