SCHEMBL7425692

SCHEMBL7425692

CCCCCOc1c(N(CC)CC)ccc2oc3ccccc3c(=O)c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.45
KCNA3 P22001 1/20 0.44
MAOA P21397 1/20 0.41
ACSL1 P33121 2/20 0.41
ACSL6 Q9UKU0 2/20 0.41
TOP2A P11388 3/20 0.41
HRH3 Q9Y5N1 5/20 0.40
MAOB P27338 4/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
MLNR O43193 1/20 0.39
CACNA1F O60840 1/20 0.39
PHF2 O75151 1/20 0.39
ABCB11 O95342 1/20 0.39
ALDH1A1 P00352 1/20 0.39
NR3C1 P04150 1/20 0.39
ERBB2 P04626 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
FYN P06241 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7379709 0.78 MAOA (0.53) XDHMAOAALDH1A1CYP3A4SMN1; SMN2
SCHEMBL7237938 0.77 PGAM1 (0.50) XDHMAOATOP2ABCHEACHE
SCHEMBL28198664 0.76 MAOA (0.62) XDHKCNA3MAOATOP2AALDH1A1
SCHEMBL27347698 0.73 KCNA3 (0.78) KCNA3ALDH1A1TP53ABCB1CYP3A4
SCHEMBL8782565 0.72 KCNA3 (0.76) KCNA3ALDH1A1TP53ABCB1CYP3A4
SCHEMBL20594363 0.72 ACSL1 (0.72) XDHMAOAACSL1ACSL6HRH3
SCHEMBL20594290 0.72 ACSL1 (0.72) XDHMAOAACSL1ACSL6HRH3
SCHEMBL20594368 0.72 ACSL1 (0.72) XDHMAOAACSL1ACSL6HRH3
SCHEMBL20594883 0.72 ACSL1 (0.72) XDHMAOAACSL1ACSL6HRH3
SCHEMBL7237937 0.71 MAOA (0.53) XDHMAOATOP2ABCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001041773-A1 XANTHONE ANALOGS FOR TREATING INFECTIOUS DISEASES AND COMPLEXATION OF HEME AND PORPHYRINS INTERLAB, INC. (US) 2001-06-14 WO disclosed