Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SELP | P16109 | 2/20 | 0.40 |
| ▸ | SELE | P16581 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437982 | 0.84 | POLB (0.44) | POLBNPC1RAB9AALDH1A1HDAC3 | |
| SCHEMBL7425861 | 0.81 | SELP (0.60) | POLBNPC1RAB9AALDH1A1SELP | |
| SCHEMBL7433695 | 0.81 | SELL (0.48) | POLBNPC1RAB9AALDH1A1SELP | |
| SCHEMBL7434272 | 0.81 | SELL (0.60) | NPC1RAB9AALDH1A1SELPSELE | |
| SCHEMBL27498211 | 0.77 | POLB (0.54) | POLBALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7436413 | 0.77 | SELP (0.46) | POLBNPC1RAB9AALDH1A1SELP | |
| SCHEMBL7432725 | 0.73 | KDM4E (0.57) | POLBNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL7438449 | 0.72 | PTPN1 (0.52) | ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL7438717 | 0.72 | ALOX15 (0.50) | POLBHDAC1SELPSELESELL | |
| SCHEMBL7439101 | 0.71 | CA12 (0.52) | POLBALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |