Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 10/20 | 0.58 |
| ▸ | F2 | P00734 | 6/20 | 0.58 |
| ▸ | DPP4 | P27487 | 2/20 | 0.53 |
| ▸ | MC4R | P32245 | 2/20 | 0.45 |
| ▸ | MC1R | Q01726 | 2/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | F12 | P00748 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702655 | 0.88 | F11 (0.65) | F11F2F10F12PRSS1 | |
| SCHEMBL6438985 | 0.86 | F2 (0.56) | F11F2DPP3 | |
| SCHEMBL6438987 | 0.86 | F2 (0.56) | F11F2DPP3 | |
| SCHEMBL24645591 | 0.83 | F11 (0.63) | F11F2F10F12PRSS1 | |
| SCHEMBL21429784 | 0.83 | F11 (0.63) | F11F2F10F12PRSS1 | |
| Trifluoroacetic Acid SCHEMBL27886446 | 0.81 | F11 (0.62) | F11F2DPP4F10F12 | |
| SCHEMBL29498112 | 0.79 | DPP4 (0.65) | DPP4MC4RMC1RMC3RDPP3 | |
| SCHEMBL3973366 | 0.79 | F11 (0.67) | F11F2F10F12PRSS1 | |
| SCHEMBL29481406 | 0.78 | F11 (0.56) | F11F2F10F12PRSS1 | |
| SCHEMBL23013213 | 0.78 | F11 (0.56) | F11F2F10F12PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |