Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426180 | 1.00 | ITGB3 (0.35) | ITGB3ITGB1ITGAVITGA5ACE | |
| SCHEMBL11104778 | 0.90 | LMNA (0.38) | ACEPOLBHPGDSMN1; SMN2 | |
| SCHEMBL11104772 | 0.90 | LMNA (0.38) | ACEPOLBHPGDSMN1; SMN2 | |
| SCHEMBL11109004 | 0.88 | ALDH1A1 (0.37) | HPGD | |
| SCHEMBL7431619 | 0.88 | ALDH1A1 (0.37) | HPGD | |
| SCHEMBL11114124 | 0.86 | ACE (0.35) | ACE | |
| SCHEMBL11114123 | 0.86 | ACE (0.35) | ACE | |
| SCHEMBL11111836 | 0.82 | ACE (0.35) | ACE | |
| SCHEMBL11111840 | 0.82 | ACE (0.35) | ACE | |
| SCHEMBL11107888 | 0.81 | LMNA (0.35) | ACEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120728-A1 | Thiazine and thiazepine containing compounds | E.R. Squibb & Sons, Inc. (US) | 1984-10-03 | — | — | EP | disclosed |
| US-4460579-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-17 | — | — | US | disclosed |