Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.68 |
| ▸ | MMP2 | P08253 | 18/20 | 0.68 |
| ▸ | MMP1 | P03956 | 9/20 | 0.68 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999031 | 0.89 | MMP9 (0.66) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL7598899 | 0.89 | MMP9 (0.66) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL7999034 | 0.81 | MMP9 (1.00) | MMP9MMP2MMP1 | |
| SCHEMBL7598904 | 0.81 | MMP9 (1.00) | MMP9MMP2MMP1 | |
| SCHEMBL7426245 | 0.81 | MMP9 (0.70) | MMP9MMP2MMP1 | |
| SCHEMBL7599808 | 0.79 | MMP9 (0.55) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL8000592 | 0.74 | MMP9 (0.52) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL7990004 | 0.69 | EPHX2 (0.48) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL7583731 | 0.69 | MMP9 (0.45) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL7598896 | 0.68 | MMP9 (0.64) | MMP9MMP2MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000044739-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |