Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 14/20 | 0.55 |
| ▸ | MMP2 | P08253 | 10/20 | 0.55 |
| ▸ | MMP1 | P03956 | 7/20 | 0.55 |
| ▸ | MMP14 | P50281 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426236 | 0.79 | MMP9 (0.68) | MMP9MMP2MMP1MMP14 | |
| SCHEMBL7600749 | 0.79 | MMP9 (0.43) | MMP9MMP2MMP1MMP14MMP13 | |
| SCHEMBL7600044 | 0.78 | MMP9 (0.52) | MMP9MMP2MMP1MMP14MMP13 | |
| SCHEMBL7599651 | 0.78 | MMP9 (0.52) | MMP9MMP2MMP1MMP14MMP13 | |
| SCHEMBL7999031 | 0.73 | MMP9 (0.66) | MMP9MMP2MMP1MMP14MMP13 | |
| SCHEMBL7598899 | 0.73 | MMP9 (0.66) | MMP9MMP2MMP1MMP14MMP13 | |
| SCHEMBL7603274 | 0.72 | MMP9 (0.47) | MMP9MMP2MMP1MMP14MMP13 | |
| SCHEMBL7426245 | 0.72 | MMP9 (0.70) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7598904 | 0.71 | MMP9 (1.00) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7999034 | 0.71 | MMP9 (1.00) | MMP9MMP2MMP1MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-B1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2002-11-20 | — | — | EP | claimed |