Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.43 |
| ▸ | TUBB | P07437 | 4/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282581 | 0.87 | TSHR (0.54) | MAPK1PDK1KDM4EALDH1A1KMT2A | |
| Ethylene SCHEMBL6410194 | 0.85 | TSHR (0.51) | MAPK1PDK1KDM4EALDH1A1KMT2A | |
| SCHEMBL14448350 | 0.83 | MAPK1 (0.53) | MAPK1ALDH1A1 | |
| SCHEMBL3854017 | 0.81 | TUBB4A (0.48) | MAPK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3247280 | 0.80 | CYP3A4 (0.49) | MAPK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7380165 | 0.79 | TUBB1 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8323174 | 0.79 | SMPD1 (0.48) | MAPK1ALDH1A1 | |
| SCHEMBL8337903 | 0.79 | SMPD1 (0.48) | MAPK1ALDH1A1 | |
| SCHEMBL14448347 | 0.79 | TSHR (0.50) | MAPK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14713356 | 0.77 | TSHR (0.48) | MAPK1PDK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |