Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290042 | 0.83 | HDAC8 (0.63) | MTORHDAC1HDAC2GRM5TP53BP1 | |
| SCHEMBL1926964 | 0.80 | MTOR (0.52) | MTORHDAC1HDAC2GRM5TP53BP1 | |
| SCHEMBL281 | 0.79 | TSHR (0.57) | HDAC1HDAC2GRM5NPC1RAB9A | |
| SCHEMBL29732178 | 0.79 | TSHR (0.57) | HDAC1HDAC2GRM5NPC1RAB9A | |
| SCHEMBL7451795 | 0.79 | TSHR (0.57) | HDAC1HDAC2GRM5NPC1RAB9A | |
| SCHEMBL17680606 | 0.79 | NPSR1 (0.59) | MTORHDAC1HDAC2GRM5TP53BP1 | |
| SCHEMBL27477217 | 0.79 | RAB9A (0.68) | MEN1KMT2ANPC1RAB9ARXFP1 | |
| Hydrochloric Acid SCHEMBL11231916 | 0.78 | TSHR (0.55) | HDAC1HDAC2GRM5NPC1RAB9A | |
| SCHEMBL7557230 | 0.77 | MTOR (0.50) | MTORHDAC1HDAC2GRM5TP53BP1 | |
| SCHEMBL31010846 | 0.77 | MTOR (0.50) | MTORHDAC1HDAC2GRM5TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068417-A3 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | SLASSI ABDELMALIK (CA) | 2002-11-14 | — | — | WO | disclosed |