Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676540 | 0.87 | BRD4 (0.51) | KMT2ATSHRALDH1A1MEN1HPGD | |
| SCHEMBL5226057 | 0.77 | ADORA2A (0.56) | HPGDHSD17B10ADORA2AADORA2B | |
| SCHEMBL7088461 | 0.76 | TLR7 (0.50) | KMT2ATSHRALDH1A1MEN1HPGD | |
| SCHEMBL7680197 | 0.76 | TLR7 (0.48) | KMT2ATSHRALDH1A1MEN1HPGD | |
| SCHEMBL7090838 | 0.75 | TLR7 (0.50) | KMT2ATSHRMEN1HPGDADORA2A | |
| SCHEMBL7416418 | 0.75 | PDE4B (0.53) | HSD17B10 | |
| SCHEMBL11017605 | 0.74 | ADORA2A (0.51) | HPGDHSD17B10ADORA2AADORA2BMAPT | |
| SCHEMBL3229725 | 0.73 | ADORA2A (0.47) | ADORA2AADORA2B | |
| SCHEMBL7091342 | 0.72 | KDM4E (0.42) | KMT2ATSHRALDH1A1MEN1HPGD | |
| SCHEMBL7953405 | 0.71 | ADORA2A (0.41) | KMT2ATSHRALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799040-A4 | TRISUBSTITUTED THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | disclosed |
| EP-0799040-A1 | TRISUBSTITUTED THIOXANTHINES | Euroceltique S.A. (LU) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018400-A1 | TRISUBSTITUTED THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |