Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955639 | 0.94 | ADORA2A (0.42) | ADORA2AADORA2BADORA1TLR7TLR8 | |
| SCHEMBL3229725 | 0.88 | ADORA2A (0.47) | ADORA2AADORA2BADORA1 | |
| SCHEMBL3111144 | 0.85 | ADORA2B (0.48) | ADORA2AADORA2BADORA1ALDH1A1TSHR | |
| SCHEMBL7091169 | 0.85 | ADORA2B (0.48) | ADORA2AADORA2BADORA1ALDH1A1TSHR | |
| SCHEMBL7091342 | 0.84 | KDM4E (0.42) | ADORA2AADORA2BADORA1TLR7ALDH1A1 | |
| SCHEMBL7680197 | 0.83 | TLR7 (0.48) | TLR7ALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL7091149 | 0.81 | P2RX3 (0.41) | ADORA2AADORA2BADORA1TLR7ALDH1A1 | |
| SCHEMBL7093461 | 0.81 | P2RX3 (0.41) | ADORA2AADORA2BADORA1TLR7ALDH1A1 | |
| SCHEMBL8412329 | 0.81 | TRAP1 (0.43) | TLR7ALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL7676540 | 0.81 | BRD4 (0.51) | TLR7ALDH1A1TSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268373-B1 | ENZYME INHIBITORS | EURO-CELTIQUE S.A. (LU) | 2001-07-31 | — | — | US | disclosed |