Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280901 | 0.81 | REN (0.47) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL6976760 | 0.81 | REN (0.47) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL14521707 | 0.75 | TBXAS1 (0.48) | TBXAS1ALDH1A1NAMPT | |
| SCHEMBL7426636 | 0.75 | HRH4 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL6840156 | 0.71 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL10772703 | 0.70 | TBXAS1 (0.66) | TBXAS1SMN1; SMN2ALDH1A1HPGDDUSP3 | |
| SCHEMBL9556789 | 0.70 | HRH4 (0.61) | CYP1A2CYP3A4CYP2D6TBXAS1SMN1; SMN2 | |
| SCHEMBL7305085 | 0.70 | HRH4 (0.61) | CYP1A2CYP3A4CYP2D6TBXAS1SMN1; SMN2 | |
| SCHEMBL7305090 | 0.70 | HRH4 (0.61) | CYP1A2CYP3A4CYP2D6TBXAS1SMN1; SMN2 | |
| SCHEMBL9432392 | 0.70 | EGLN3 (0.47) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |