Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428713 | 0.85 | CTSS (0.51) | MEN1KMT2ANPSR1 | |
| SCHEMBL7434982 | 0.82 | CTSS (0.58) | MEN1KMT2ANPSR1CYP2C9CYP2C19 | |
| SCHEMBL6447335 | 0.80 | MEN1 (0.63) | MEN1KMT2ANPSR1ALDH1A1CYP2C9 | |
| SCHEMBL19691757 | 0.79 | KMT2A (0.73) | MEN1KMT2ANPSR1ALDH1A1CYP2C19 | |
| SCHEMBL24658483 | 0.78 | GAA (0.61) | MEN1KMT2ANPSR1PREPLIPE | |
| SCHEMBL7391841 | 0.77 | CTSK (0.56) | MEN1KMT2ANPSR1 | |
| SCHEMBL7159251 | 0.75 | PREP (0.59) | MEN1KMT2ANPSR1ALDH1A1PREP | |
| SCHEMBL11263011 | 0.75 | PREP (0.59) | MEN1KMT2ANPSR1ALDH1A1PREP | |
| SCHEMBL2968474 | 0.75 | GAA (0.53) | MEN1KMT2ANPSR1ALDH1A1PREP | |
| SCHEMBL6044214 | 0.75 | MEN1 (0.57) | MEN1KMT2ANPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |