Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434982 | 0.92 | CTSS (0.58) | CTSSCTSBCTSKCTSLMEN1 | |
| SCHEMBL7438999 | 0.88 | CTSS (0.55) | CTSSCTSBCTSKCAPN1CA2 | |
| SCHEMBL7426669 | 0.85 | MEN1 (0.57) | MEN1KMT2ANPSR1 | |
| SCHEMBL7388307 | 0.84 | CTSK (0.51) | CTSSCTSBCTSKCAPN1CTSL | |
| SCHEMBL8893671 | 0.83 | CTSS (0.55) | CTSSCTSBCTSKCTSL | |
| SCHEMBL8895231 | 0.83 | CTSS (0.55) | CTSSCTSBCTSKCTSL | |
| SCHEMBL27514276 | 0.82 | CCR1 (0.65) | CTSSCTSBCTSKCAPN1CTSL | |
| SCHEMBL8893516 | 0.81 | CASP3 (0.51) | CTSSCTSBCTSKCAPN1CTSL | |
| SCHEMBL26291080 | 0.79 | CTSL (0.59) | CTSSCTSBCTSKCA2CA5A | |
| SCHEMBL26291260 | 0.79 | CTSL (0.59) | CTSSCTSBCTSKCA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |