Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 8/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425039 | 0.95 | ITGB1 (0.54) | ITGA4ITGB1ACHESIGMAR1KMT2A | |
| SCHEMBL7430007 | 0.89 | ITGB1 (0.49) | ITGA4ITGB1ACHEKMT2AMEN1 | |
| SCHEMBL7431414 | 0.89 | ACHE (0.54) | ITGA4ITGB1ACHESIGMAR1KMT2A | |
| SCHEMBL7430185 | 0.88 | ITGB1 (0.45) | ITGA4ITGB1ACHESIGMAR1KMT2A | |
| SCHEMBL7390416 | 0.85 | ITGA4 (0.52) | ITGA4ITGB1SIGMAR1KMT2AMEN1 | |
| SCHEMBL7429580 | 0.84 | ITGB1 (0.47) | ITGA4ITGB1ACHEKMT2AMEN1 | |
| SCHEMBL7539587 | 0.83 | ACHE (0.47) | ITGA4ITGB1ACHESIGMAR1KMT2A | |
| SCHEMBL7425433 | 0.83 | ACHE (0.52) | ITGA4ITGB1ACHESIGMAR1KMT2A | |
| SCHEMBL7432383 | 0.82 | ITGB1 (0.45) | ITGA4ITGB1ACHEKMT2AMEN1 | |
| SCHEMBL7429192 | 0.82 | ITGB1 (0.53) | ITGA4ITGB1KMT2ACCR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |