Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776022 | 0.82 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL14685207 | 0.80 | HSD11B1 (0.60) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14685202 | 0.80 | HSD11B1 (0.60) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4940460 | 0.79 | HSD11B1 (0.58) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2709699 | 0.76 | HTR3A (0.63) | HSD11B1MEN1KMT2A | |
| SCHEMBL7429437 | 0.75 | KMT2A (0.65) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29689100 | 0.75 | HTR3A (0.62) | HSD11B1MEN1KMT2A | |
| SCHEMBL9369612 | 0.75 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4428154 | 0.75 | HSD11B1 (0.58) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30937200 | 0.74 | SMN1; SMN2 (0.50) | HSD11B1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256665-A | Process for preparing new 2-piperazinylbenzimidazole | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1993-10-26 | — | — | US | claimed |
| EP-0512939-A1 | New 2-piperazinylbenzimidazole derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-11-11 | — | — | EP | claimed |
| EP-0512939-B1 | 2-piperazinylbenzimidazole derivatives | ESPANOLA PROD QUIMICOS (ES) | 1999-08-25 | — | — | EP | disclosed |
| US-5256665-A | Process for preparing new 2-piperazinylbenzimidazole | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1993-10-26 | — | — | US | disclosed |
| EP-0512939-A1 | New 2-piperazinylbenzimidazole derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-11-11 | — | — | EP | disclosed |