Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685202 | 0.87 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL14685207 | 0.87 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL4940460 | 0.86 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL2709699 | 0.83 | HTR3A (0.63) | HSD11B1 | |
| SCHEMBL7427136 | 0.82 | HSD11B1 (0.56) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL29689100 | 0.81 | HTR3A (0.62) | HSD11B1 | |
| SCHEMBL4428154 | 0.81 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL6551438 | 0.81 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL7166739 | 0.81 | — | — | |
| SCHEMBL7166738 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | claimed |
| EP-1308439-B1 | PROLINE DERIVATIVES AND USE THEREOF AS DRUGS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-0641784-B1 | BENZIMIDAZOLE DERIVATIVE, PRODUCTION THEREOF, ANTIEMETIC CONTAINING SAME AS ACTIVE INGREDIENT, AND INTERMEDIATE FOR PRODUCING SAME | KANEBO LTD (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5407936-A | For vomiting due to chemotherapy with cisplatin | KANEBO LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0641784-A1 | BENZIMIDAZOLE DERIVATIVE, PRODUCTION THEREOF, ANTIEMETIC CONTAINING SAME AS ACTIVE INGREDIENT, AND INTERMEDIATE FOR PRODUCING SAME | KANEBO, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0079545-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KANEBO, LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |
| US-4430343-A | ANTIHISTAMINES | KANEBO, LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | disclosed |