Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.58 |
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | LAP3 | P28838 | 3/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692780 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BANPEPRNPEPDNPEP | |
| SCHEMBL3508825 | 0.87 | MMP2 (0.55) | ANPEPRNPEPDNPEPMMP2LAP3 | |
| SCHEMBL5568037 | 0.83 | MMP2 (0.69) | MTNR1AMTNR1BMMP2ALPIPKM | |
| SCHEMBL3055735 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BANPEPRNPEPDNPEP | |
| SCHEMBL3039933 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BANPEPRNPEPDNPEP | |
| SCHEMBL12452003 | 0.80 | IDO1 (0.52) | ANPEPRNPEPDNPEPMMP2LAP3 | |
| SCHEMBL3039937 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BANPEPRNPEPDNPEP | |
| SCHEMBL3055737 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BANPEPRNPEPDNPEP | |
| SCHEMBL7277645 | 0.78 | MTNR1A (0.55) | MTNR1AMTNR1BANPEPRNPEPDNPEP | |
| SCHEMBL15638183 | 0.78 | ALPI (0.56) | ANPEPRNPEPDNPEPMMP2ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709032-A | VASODILATION AND HYPOTENSIVE AGENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1987-11-24 | — | — | US | disclosed |
| US-4634770-A | VASODILATORS, HYPOTENSIVES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1987-01-06 | — | — | US | disclosed |
| EP-0109023-A1 | Isoquinolinesulfonamide derivatives and process for the preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-05-23 | — | — | EP | disclosed |