Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364532 | 0.91 | POLB (0.43) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL7431822 | 0.88 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL8984936 | 0.87 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL9364015 | 0.84 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL7492934 | 0.82 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL9363808 | 0.81 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL9364248 | 0.80 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL9364676 | 0.80 | KDM4E (0.53) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL9364528 | 0.80 | NPSR1 (0.45) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 | |
| SCHEMBL9363990 | 0.79 | ALDH1A1 (0.47) | HSP90AA1HSP90AB1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551663-A1 | Dimethyl 2,6-dimethyl-1n-propyl-4-(4-trifluormethylphenyl)-1,4-dihydro-pyridine-3,5-dicarboxylate, method for its production and its pharmaceutical use | BAYER AG (DE) | 1993-07-21 | — | — | EP | claimed |
| EP-0551663-A1 | Dimethyl 2,6-dimethyl-1n-propyl-4-(4-trifluormethylphenyl)-1,4-dihydro-pyridine-3,5-dicarboxylate, method for its production and its pharmaceutical use | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |
| EP-0551663-A1 | Dimethyl 2,6-dimethyl-1n-propyl-4-(4-trifluormethylphenyl)-1,4-dihydro-pyridine-3,5-dicarboxylate, method for its production and its pharmaceutical use | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |