Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CAD | P27708 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768440 | 0.83 | CAD (0.40) | L3MBTL1GAAHSD17B10MGAMSI | |
| SCHEMBL1841018 | 0.81 | CAD (0.41) | L3MBTL1GAAHSD17B10MGAMSI | |
| SCHEMBL21381783 | 0.81 | CAD (0.41) | L3MBTL1GAAHSD17B10MGAMSI | |
| SCHEMBL4984189 | 0.81 | L3MBTL1 (0.46) | L3MBTL1GAAHSD17B10MGAMSI | |
| Hydrochloric Acid SCHEMBL23522225 | 0.79 | CAD (0.40) | L3MBTL1GAAHSD17B10MGAMSI | |
| Hydrochloric Acid SCHEMBL30161768 | 0.79 | CAD (0.40) | L3MBTL1GAAHSD17B10MGAMSI | |
| SCHEMBL10523453 | 0.78 | CAD (0.39) | L3MBTL1GAATSHRHSD17B10MGAM | |
| SCHEMBL2327658 | 0.77 | KMT2A (0.54) | GAAKMT2APOLBKDRALDH1A1 | |
| SCHEMBL11186485 | 0.76 | GAA (0.48) | L3MBTL1GAATSHRMGAMSI | |
| SCHEMBL17385231 | 0.75 | CPB2 (0.46) | L3MBTL1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003846-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1003846-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1998050533-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |