SCHEMBL7760696

SCHEMBL7760696

Cc1ccccc1NC(=S)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.75
L3MBTL1 Q9Y468 2/20 0.75
LMNA P02545 2/20 0.75
MEN1 O00255 1/20 0.75
KMT2A Q03164 1/20 0.75
CYP3A4 P08684 2/20 0.65
TAS2R38 P59533 1/20 0.65
HSD17B10 Q99714 1/20 0.65
HPGD P15428 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
KDM4E B2RXH2 2/20 0.60
HTT P42858 1/20 0.60
EPHX1 P07099 2/20 0.59
NPSR1 Q6W5P4 1/20 0.58
ALOX12 P18054 1/20 0.57
MAPT P10636 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11598073 1.00 ALDH1A1 (0.75) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL29522293 0.90 L3MBTL1 (0.70) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL1276741 0.90 L3MBTL1 (0.70) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL8613443 0.84 ALDH1A1 (0.69) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL17084267 0.84 ALDH1A1 (0.60) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL17079615 0.83 ALDH1A1 (0.68) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL16566574 0.82 ALDH1A1 (0.65) ALDH1A1MEN1KMT2ANPSR1ALOX12
SCHEMBL5154921 0.82 ALDH1A1 (0.64) ALDH1A1L3MBTL1LMNAMEN1KMT2A
SCHEMBL132620 0.81 ALDH1A1 (1.00) ALDH1A1LMNAMEN1KMT2ACYP3A4
SCHEMBL20026950 0.81 LMNA (0.72) ALDH1A1LMNAMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10253256-B2 Use of sulfur and selenium compounds as precursors to nanostructured materials THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-04-09 US claimed
US-20160237345-A1 USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-08-18 US claimed
EP-3049370-A1 USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS The Trustees of Columbia University in the City of New York (US) 2016-08-03 EP claimed
US-10767112-B2 Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-09-08 US disclosed
US-10767112-B2 Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-09-08 US disclosed
US-10253256-B2 Use of sulfur and selenium compounds as precursors to nanostructured materials THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-04-09 US disclosed
US-20170369779-A1 METHODS OF PRODUCING METAL SULFIDES, METAL SELENIDES, AND METAL SULFIDES/SELENIDES HAVING CONTROLLED ARCHITECTURES USING KINETIC CONTROL THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-12-28 US disclosed
US-20170369779-A1 METHODS OF PRODUCING METAL SULFIDES, METAL SELENIDES, AND METAL SULFIDES/SELENIDES HAVING CONTROLLED ARCHITECTURES USING KINETIC CONTROL THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-12-28 US disclosed
US-20160237345-A1 USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-08-18 US disclosed
EP-3049370-A1 USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS The Trustees of Columbia University in the City of New York (US) 2016-08-03 EP disclosed
US-9194805-B2 Trace detection of analytes using portable raman systems SANDIA CORPORATION (US) 2015-11-24 US disclosed
US-20150062576-A1 TRACE DETECTION OF ANALYTES USING PORTABLE RAMAN SYSTEMS NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2015-03-05 US disclosed
EP-0521706-B1 Heat-sensitive color recording material FUJI PHOTO FILM CO LTD (JP) 2001-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10253256-B2 Use of sulfur and selenium compounds as precursors to nanostructured materials SCLY, TST, SOD1 ALDH1A1 1898/4885L3MBTL1 3952/4885LMNA 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.