Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.44 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | PPARD | Q03181 | 8/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440588 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2HDAC1ALDH1A1HTTNAMPT | |
| SCHEMBL10444059 | 0.84 | ACE (0.49) | — | |
| SCHEMBL10444057 | 0.84 | ACE (0.49) | — | |
| SCHEMBL10444056 | 0.83 | KLK5 (0.49) | ALDH1A1L3MBTL1 | |
| SCHEMBL7425049 | 0.78 | HDAC1 (0.40) | HDAC1NAMPTL3MBTL1 | |
| SCHEMBL7435753 | 0.76 | HDAC1 (0.40) | HDAC1NAMPTL3MBTL1 | |
| SCHEMBL30932891 | 0.76 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13594013 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2HDAC1NAMPTL3MBTL1 | |
| SCHEMBL19423686 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2HDAC1ALDH1A1HTTNAMPT | |
| SCHEMBL7428737 | 0.73 | FFAR1 (0.44) | FFAR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |