Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.44 |
| ▸ | PPARG | P37231 | 12/20 | 0.44 |
| ▸ | PPARD | Q03181 | 12/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444215 | 0.83 | ACE (0.44) | — | |
| SCHEMBL7425055 | 0.78 | TP53 (0.32) | — | |
| SCHEMBL7435758 | 0.76 | TP53 (0.34) | FFAR1PPARGPPARD | |
| SCHEMBL7684870 | 0.74 | EDNRA (0.57) | — | |
| SCHEMBL7428732 | 0.73 | SMN1; SMN2 (0.44) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL7438336 | 0.72 | EDNRA (0.39) | — | |
| SCHEMBL10443920 | 0.71 | PPARG (0.50) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL9628106 | 0.71 | PPARD (0.56) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL25146389 | 0.70 | PPARG (0.55) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL6214519 | 0.69 | FFAR1 (0.59) | FFAR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |