Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431183 | 0.82 | FFAR1 (0.39) | FFAR1CA1CA2PPARDPPARG | |
| SCHEMBL7424900 | 0.79 | PPARA (0.45) | FFAR1PPARDPPARG | |
| SCHEMBL7430025 | 0.78 | MAPT (0.44) | SLC10A2MAPTFFAR1 | |
| SCHEMBL7426297 | 0.78 | CYP1A2 (0.40) | MAPTHIF1ACA9CA12 | |
| SCHEMBL7435758 | 0.72 | TP53 (0.34) | FFAR1PPARDPPARG | |
| SCHEMBL29509616 | 0.71 | CA9 (0.46) | SLC10A2CA9CA12CA1CA2 | |
| SCHEMBL7437211 | 0.70 | PPARA (0.42) | FFAR1PPARDPPARG | |
| SCHEMBL6670411 | 0.70 | FFAR1 (0.60) | FFAR1PPARD | |
| SCHEMBL7437531 | 0.70 | CA9 (0.40) | SLC10A2CA9CA12CA1CA2 | |
| SCHEMBL10011520 | 0.69 | PPARG (0.59) | FFAR1PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |
| EP-0350163-A2 | Renin inhibitory peptides | BEECHAM GROUP PLC (GB) | 1990-01-10 | — | — | EP | disclosed |