Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | SFN | P31947 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7433216 | 0.91 | MEN1 (0.42) | KDM4ECA1CA2LMNAMEN1 | |
| SCHEMBL7428892 | 0.82 | ST14 (0.54) | KDM4EF13A1SFN | |
| Hydrochloric Acid SCHEMBL6365976 | 0.81 | ST14 (0.53) | KDM4EF13A1SFN | |
| Hydrochloric Acid SCHEMBL7437342 | 0.78 | MEN1 (0.43) | KDM4ELMNAMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7427213 | 0.77 | LMNA (0.43) | KDM4ELMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7429245 | 0.73 | MEN1 (0.39) | KDM4ECA1CA2LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL6365784 | 0.73 | ST14 (0.53) | — | |
| SCHEMBL7116195 | 0.68 | ST14 (0.55) | KDM4EF13A1ESRRBESRRG | |
| Hydrochloric Acid SCHEMBL7491587 | 0.68 | SIRT2 (0.49) | KDM4ELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7539002 | 0.67 | ST14 (0.54) | KDM4EF13A1ESRRBESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206444-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | Morphochem AG (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014320-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2001-03-01 | — | — | WO | disclosed |