SCHEMBL7429057

SCHEMBL7429057

O=C(O)[C@H](CO)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
GAA P10253 2/20 0.70
POLB P06746 4/20 0.68
KDM4E B2RXH2 1/20 0.68
TP53 P04637 1/20 0.68
GLA P06280 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2D6 P10635 1/20 0.68
HPGD P15428 1/20 0.68
ALOX12 P18054 1/20 0.68
NFKB1 P19838 1/20 0.68
APEX1 P27695 1/20 0.68
MAPK1 P28482 1/20 0.68
HSD17B10 Q99714 1/20 0.68
L3MBTL1 Q9Y468 2/20 0.57
HIF1A Q16665 1/20 0.56
AADAT Q8N5Z0 1/20 0.54
DNMT1 P26358 7/20 0.54
KMT2A Q03164 2/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22502343 1.00 ALDH1A1 (0.70) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL14680937 1.00 ALDH1A1 (0.70) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL6896852 0.86 ALDH1A1 (0.79) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL6896845 0.86 ALDH1A1 (0.79) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL512529 0.84 ALDH1A1 (0.71) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL22513798 0.84 ALDH1A1 (0.69) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL20835844 0.84 ALDH1A1 (0.68) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL512864 0.84 ALDH1A1 (0.68) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL4903634 0.84 ALDH1A1 (0.68) ALDH1A1GAAPOLBKDM4ETP53
SCHEMBL7288420 0.84 ALDH1A1 (0.71) ALDH1A1GAAPOLBKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4562263-A HYPOTENSIVE AND HYDERTENSIVE AGENTS, ANTIDEPRESSANTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-31 US claimed
EP-0128684-A1 Process for producing 3-(3,4-dihydroxyphenyl) serine SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1984-12-19 EP claimed
WO-2020206381-A1 CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS AND METHODS OF USING AND MAKING SAME SUTTON LARRY D (US) 2020-10-08 WO disclosed
WO-2020206381-A1 CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS AND METHODS OF USING AND MAKING SAME SUTTON LARRY D (US) 2020-10-08 WO disclosed
US-5688434-A BLEACHING TEXTILES BY APPLYING BLEACHING AGENT AUSIMONT S.P.A. (IT) 1997-11-18 US disclosed
US-5520844-A Imide-aromatic peroxyacids as bleaching agents AUSIMONT S.P.A. (IT) 1996-05-28 US disclosed
EP-0325288-B1 IMIDO-AROMATIC PERCARBOXYLIC ACIDS AUSIMONT S.p.A. (IT) 1993-09-01 EP disclosed
EP-0325289-B1 BLEACHING AGENTS COMPRISING IMIDO-AROMATIC PERCARBOXYLIC ACIDS AUSIMONT S.p.A. (IT) 1993-09-01 EP disclosed
EP-0325289-A1 Bleaching agents comprising imido-aromatic percarboxylic acids AUSIMONT S.p.A. (IT) 1989-07-26 EP disclosed
EP-0325288-A1 Imido-aromatic percarboxylic acids AUSIMONT S.p.A. (IT) 1989-07-26 EP disclosed
US-4704385-A MONOCYCLIC BETA-LACTAM ANTIBIOTICS BEECHAM GROUP P.L.C. (GB) 1987-11-03 US disclosed
US-4678782-A ANTIBIOTICS BEECHAM GROUP P.L.C. (GB) 1987-07-07 US disclosed
US-4647558-A MONOCYCLIC B-LACTAM ANTIBIOTIC BEECHAM GROUP P.L.C. (GB) 1987-03-03 US disclosed
EP-0088488-B1 ANTIBACTERIAL AGENTS, THEIR PREPARATION AND USE BEECHAM GROUP PLC (GB) 1986-10-01 EP disclosed
US-4595532-A N-(substituted-methyl)-azetidin-2-ones UNIVERSITY OF NOTRE DAME DU LAC (US) 1986-06-17 US disclosed
EP-0116432-A2 Improvements in or relating to N-(substituted-methyl)-azetidin-2-ones THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1984-08-22 EP disclosed
EP-0088488-A1 Antibacterial agents, their preparation and use BEECHAM GROUP PLC (GB) 1983-09-14 EP disclosed
EP-0086563-A1 Antibacterial agents, their preparation and use BEECHAM GROUP PLC (GB) 1983-08-24 EP disclosed